Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Nanobody Names | Anti-Ccn Family Member 2 nanobodyAnti-Cellular Communication Network Factor 2 nanobodyAnti-Connective Tissue Growth Factor nanobodyAnti-Hypertrophic Chondrocyte-Specific Protein 24 nanobodyAnti-Insulin-Like Growth Factor-Binding Protein 8 nanobodyAnti-Ibp-8 nanobodyAnti-Igf-Binding Protein 8 nanobodyAnti-Igfbp-8 nanobodyAnti-CCN2 nanobodyAnti-CTGF nanobodyAnti-HCS24 nanobodyAnti-IGFBP8 nanobody |
Information sourced from Uniprot.org