Anti-CTBP1 antibody (388-437 aa) (STJ92513)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CtBP1 at the amino acid range 388-437
General Information
| Short Description | Rabbit polyclonal anti-C-terminal-binding protein 1 (388-437 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CTBP1 |
| Gene ID | 1487 |
| Uniprot ID | CTBP1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CtBP1 at the amino acid range 388-437 |
| Immunogen Region | 388-437 aa |
| Specificity | CtBP1 Polyclonal Antibody detects endogenous levels of CtBP1 protein. |
Additional Info
| Post Translational Modifications | The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation. ADP-ribosylated.when cells are exposed to brefeldin A. Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4. |
| Function | Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. |
| Protein Name | C-Terminal-Binding Protein 1Ctbp1 |
| Database Links | Reactome: R-HSA-3769402Reactome: R-HSA-3899300Reactome: R-HSA-4641265Reactome: R-HSA-5339700 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-C-Terminal-Binding Protein 1 antibodyAnti-Ctbp1 antibodyAnti-CTBP1 antibodyAnti-CTBP antibody |
Information sourced from Uniprot.org