| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CST3/cystatin C (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx. 15kDa band observed in Human Testis and Prostate lysates (calculated MW of 15.8kDa according to NP_000090.1). Recommended concentration: 0.3-1µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CST3 |
| Gene ID: | 1471 |
| Uniprot ID: | CYTC_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000090.1 |
| Immunogen Sequence: | SVEEEGVRRALD |
| Post Translational Modifications | The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21. |
| Function | As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. |
| Protein Name | Cystatin-CCystatin-3Gamma-TraceNeuroendocrine Basic PolypeptidePost-Gamma-Globulin |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cystatin-C antibodyAnti-Cystatin-3 antibodyAnti-Gamma-Trace antibodyAnti-Neuroendocrine Basic Polypeptide antibodyAnti-Post-Gamma-Globulin antibodyAnti-CST3 antibody |
Information sourced from Uniprot.org
