Anti-CSPG5 antibody (211-260) (STJ94431)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human CSPG5. AA range:211-260
General Information
| Short Description | Rabbit polyclonal anti-Chondroitin sulfate proteoglycan 5 (211-260) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CSPG5 |
| Gene ID | 10675 |
| Uniprot ID | CSPG5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CSPG5. AA range:211-260 |
| Immunogen Region | 211-260 |
| Specificity | Neuroglycan C Polyclonal Antibody detects endogenous levels of Neuroglycan C protein. |
Additional Info
| Tissue Specificity | Detected in cerebrospinal fluid (at protein level). Detected in urine (at protein level). Expressed in brain (at protein level). |
| Post Translational Modifications | N-glycosylated. O-glycosylated.contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissue maturation. Phosphorylated.in intracellular and extracellular parts. |
| Function | May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. |
| Protein Name | Chondroitin Sulfate Proteoglycan 5Acidic Leucine-Rich Egf-Like Domain-Containing Brain ProteinNeuroglycan C |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-4420332 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynaptic Cell MembraneEndoplasmic Reticulum MembraneGolgi Apparatus MembraneCell SurfaceSecretedIn NeuronsLocalizes To Synaptic JunctionsAlso Detected In The Endoplasmic Reticulum And The GolgiPartially Enriched In Lipid Rafts |
| Alternative Antibody Names | Anti-Chondroitin Sulfate Proteoglycan 5 antibodyAnti-Acidic Leucine-Rich Egf-Like Domain-Containing Brain Protein antibodyAnti-Neuroglycan C antibodyAnti-CSPG5 antibodyAnti-CALEB antibodyAnti-NGC antibody |
Information sourced from Uniprot.org