| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Chondroitin sulfate proteoglycan 5 (211-260) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CSPG5 |
| Gene ID: | 10675 |
| Uniprot ID: | CSPG5_HUMAN |
| Immunogen Region: | 211-260 |
| Specificity: | Neuroglycan C Polyclonal Antibody detects endogenous levels of Neuroglycan C protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CSPG5. AA range:211-260 |
| Tissue Specificity | Detected in cerebrospinal fluid (at protein level). Detected in urine (at protein level). Expressed in brain (at protein level). |
| Post Translational Modifications | N-glycosylated. O-glycosylated.contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissue maturation. Phosphorylated.in intracellular and extracellular parts. |
| Function | May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. |
| Protein Name | Chondroitin Sulfate Proteoglycan 5Acidic Leucine-Rich Egf-Like Domain-Containing Brain ProteinNeuroglycan C |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-4420332 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynaptic Cell MembraneEndoplasmic Reticulum MembraneGolgi Apparatus MembraneCell SurfaceSecretedIn NeuronsLocalizes To Synaptic JunctionsAlso Detected In The Endoplasmic Reticulum And The GolgiPartially Enriched In Lipid Rafts |
| Alternative Antibody Names | Anti-Chondroitin Sulfate Proteoglycan 5 antibodyAnti-Acidic Leucine-Rich Egf-Like Domain-Containing Brain Protein antibodyAnti-Neuroglycan C antibodyAnti-CSPG5 antibodyAnti-CALEB antibodyAnti-NGC antibody |
Information sourced from Uniprot.org
