• STJ73446 (0. 3µg/ml) staining of NIH3T3 (A) , HeLa (B) , K562 (C) , MCF7 (D) and HepG2 (E) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • STJ73446 (0. 3µg/ml) staining of Pig Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

Anti-CSNK2B antibody (172-186) (STJ73446)

SKU:
STJ73446-100

£312.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CSNK2B (172-186) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:128000.
WB: Approx 26kDa band observed in lysates of cell lines NIH3T3, HeLa, K562, MCF7 and HepG2, and in Pig Testis lysates (calculated MW of 24.9kDa according to Human, NP_001311.3, Mouse NP_0
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: CSNK2B
Gene ID: 1460
Uniprot ID: CSK2B_HUMAN
Immunogen Region: 172-186
Accession Number: NP_001311.3; NP_001269314.1
Specificity: This antibody is expected to recognize both reported isoforms (NP_001311.3; NP_001269314.1).
Immunogen Sequence: PEYRPKRPANQFVPR
Function Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling. (Microbial infection) Upon infection with Epstein-Barr virus (EBV), the interaction with viral EBNA1 increases the association of CK2 with PML proteins, which increases PML phosphorylation by CK2, triggering the polyubiquitylation and degradation of PML. Seems to also suppress EBV reactivation by mediating ARK2N and JUN at the Z promoter which inhibits BZLF1 transcrition.
Protein Name Casein Kinase Ii Subunit Beta
Ck Ii Beta
Phosvitin
Protein G5a
Database Links Reactome: R-HSA-1483191
Reactome: R-HSA-201688
Reactome: R-HSA-2514853
Reactome: R-HSA-445144
Reactome: R-HSA-6798695
Reactome: R-HSA-6804756
Reactome: R-HSA-6814122
Reactome: R-HSA-8934903
Reactome: R-HSA-8939243
Reactome: R-HSA-8948751
Reactome: R-HSA-9755511
Reactome: R-HSA-9828806
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Casein Kinase Ii Subunit Beta antibody
Anti-Ck Ii Beta antibody
Anti-Phosvitin antibody
Anti-Protein G5a antibody
Anti-CSNK2B antibody
Anti-CK2N antibody
Anti-G5A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance