| Short Description : | Rabbit monoclonal Cold Shock Domain-Containing Protein E1 (1-100) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4191RM |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CSDE1 |
| Gene ID: | 7812 |
| Uniprot ID: | CSDE1_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MSFDPNLLHNNGHNGYPNGT SAALRETGVIEKLLTSYGFI QCSERQARLFFHCSQYNGNL QDLKVGDDVEFEVSSDRRTG KPIAVKLVKIKQEILPEERM |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CSDE1 (NP_009089.4). |
| Function | RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Required for efficient formation of stress granules. (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA. |
| Protein Name | Cold Shock Domain-Containing Protein E1N-Ras Upstream Gene ProteinProtein Unr |
| Database Links | |
| Cellular Localisation | CytoplasmStress GranuleP-Body |
| Alternative Antibody Names | Anti-Cold Shock Domain-Containing Protein E1 antibodyAnti-N-Ras Upstream Gene Protein antibodyAnti-Protein Unr antibodyAnti-CSDE1 antibodyAnti-D1S155E antibodyAnti-KIAA0885 antibodyAnti-NRU antibodyAnti-UNR antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and CSDE1 knockout (KO) HeLa cells, using [KO Validated] CSDE1 Rabbit polyclonal antibody (STJ11100877) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89811/358276/STJ11100877_1__66900.1713122623.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CSDE1 knockout (KO) HeLa cells, using [KO Validated] CSDE1 Rabbit polyclonal antibody (STJ11100877) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.")
