• Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-CRCP antibody (STJ190768)

SKU:
STJ190768

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DNA-directed RNA polymerase III subunit RPC9 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CRCP
Gene ID: 27297
Uniprot ID: RPC9_HUMAN
Specificity: RPC9 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway. Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
Protein Name Dna-Directed Rna Polymerase Iii Subunit Rpc9
Rna Polymerase Iii Subunit C9
Calcitonin Gene-Related Peptide-Receptor Component Protein
Cgrp-Rcp
Cgrp-Receptor Component Protein
Cgrprcp
Hsc17
Database Links Reactome: R-HSA-1834949
Reactome: R-HSA-73780
Reactome: R-HSA-73980
Reactome: R-HSA-749476
Reactome: R-HSA-76061
Reactome: R-HSA-76066
Reactome: R-HSA-76071
Cellular Localisation Nucleus
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Dna-Directed Rna Polymerase Iii Subunit Rpc9 antibody
Anti-Rna Polymerase Iii Subunit C9 antibody
Anti-Calcitonin Gene-Related Peptide-Receptor Component Protein antibody
Anti-Cgrp-Rcp antibody
Anti-Cgrp-Receptor Component Protein antibody
Anti-Cgrprcp antibody
Anti-Hsc17 antibody
Anti-CRCP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance