| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Carnitine O-acetyltransferase for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CRAT |
| Gene ID: | 1384 |
| Uniprot ID: | CACP_HUMAN |
| Specificity: | This antibody detects endogenous levels of CRAT at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human CRAT |
| Function | Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation. Responsible for the synthesis of short- and branched-chain acylcarnitines. Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates. Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates. |
| Protein Name | Carnitine O-AcetyltransferaseCarnitine AcetylaseCarnitine AcetyltransferaseCatCrat |
| Database Links | Reactome: R-HSA-389887Reactome: R-HSA-9033241 |
| Cellular Localisation | Endoplasmic ReticulumPeroxisomeMitochondrion Inner MembranePeripheral Membrane ProteinMatrix SideIsoform 1: MitochondrionIsoform 2: Peroxisome |
| Alternative Antibody Names | Anti-Carnitine O-Acetyltransferase antibodyAnti-Carnitine Acetylase antibodyAnti-Carnitine Acetyltransferase antibodyAnti-Cat antibodyAnti-Crat antibodyAnti-CRAT antibodyAnti-CAT1 antibody |
Information sourced from Uniprot.org
