| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Copine-3 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPNE3 |
| Gene ID: | 8895 |
| Uniprot ID: | CPNE3_HUMAN |
| Specificity: | This antibody detects endogenous levels of CPNE3 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human CPNE3 |
| Post Translational Modifications | Phosphorylated on serine and threonine residues. |
| Function | Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation. |
| Protein Name | Copine-3Copine Iii |
| Database Links | Reactome: R-HSA-1483206Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCell MembraneCell JunctionFocal AdhesionAssociates To The Membrane In A Calcium-Dependent MannerTranslocates To The Cell Membrane And The Nucleus In A Calcium- Or Growth Factor Heregulin-Dependent MannerColocalizes With The Tyrosine Phosphorylated Erbb2 Form At Cell Membrane And Focal Adhesions In A Calcium- Or Growth Factor Heregulin-Dependent Manner |
| Alternative Antibody Names | Anti-Copine-3 antibodyAnti-Copine Iii antibodyAnti-CPNE3 antibodyAnti-CPN3 antibodyAnti-KIAA0636 antibody |
Information sourced from Uniprot.org