| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CPB2 |
| Gene ID: |
1361 |
| Uniprot ID: |
CBPB2_HUMAN |
| Immunogen Region: |
115-365 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 115-365 of human CPB2 (NP_001863.2). |
| Immunogen Sequence: |
ASASYYEQYHSLNEIYSWIE FITERHPDMLTKIHIGSSFE KYPLYVLKVSGKEQAAKNAI WIDCGIHAREWISPAFCLWF IGHITQFYGIIGQYTNLLRL VDFYVMPVVNVDGYDYSWKK NRMWRKNRSFYANNHCIGTD LNRNFASKHWCEEGASSSSC SETYCGLYPESEPEVKAVAS FLRRNINQIKAYISMHSYSQ HIVFPYSYTRSKSKDHEELS LVASEAVRAIEKTSKNTRY |
| Tissue Specificity | Plasma.synthesized in the liver. |
| Post Translational Modifications | N-glycosylated. N-glycan at Asn-108: Hex5HexNAc4. |
| Function | Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. |
| Protein Name | Carboxypeptidase B2Carboxypeptidase UCpuPlasma Carboxypeptidase BPcpbThrombin-Activable Fibrinolysis InhibitorTafi |
| Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Carboxypeptidase B2 antibodyAnti-Carboxypeptidase U antibodyAnti-Cpu antibodyAnti-Plasma Carboxypeptidase B antibodyAnti-Pcpb antibodyAnti-Thrombin-Activable Fibrinolysis Inhibitor antibodyAnti-Tafi antibodyAnti-CPB2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
