Anti-COPG2 antibody (542-871) (STJ118262)

Name: Anti-COPG2 antibody (542-871) (STJ118262)
SKU: STJ118262
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118262

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Short Description	Rabbit polyclonal COPG2 (542-871) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:100 IF/ICC:1:50-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	COPG2
Gene ID	26958
Uniprot ID	COPG2_HUMAN
Immunogen Region	542-871
Immunogen Sequence	LNATYIFNGLTVSVPGMEKA LHQYTLEPSEKPFDMKSIPL AMAPVFEQKAEITLVATKPE KLAPSRQDIFQEQLAAIPEF LNIGPLFKSSEPVQLTEAET EYFVRCIKHMFTNHIVFQFD CTNTLNDQLLEKVTVQMEPS DSYEVLSCIPAPSLPYNQPG ICYTLVRLPDDDPTAVAGSF SCTMKFTVRDCDPNTGVPDE DGYDDEYVLEDLEVTVSDHI QKVLKPNFAAAWEEVGDTF
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 542-871 of human COPG2 (NP_036265.3).

Function	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins.the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Protein Name	Coatomer Subunit Gamma-2 Gamma-2-Coat Protein Gamma-2-Cop
Database Links	Reactome: R-HSA-6807878 Reactome: R-HSA-6811434
Cellular Localisation	Cytoplasm Cytosol Golgi Apparatus Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasmic Vesicle Copi-Coated Vesicle Membrane The Coatomer Is Cytoplasmic Or Polymerized On The Cytoplasmic Side Of The Golgi As Well As On The Vesicles/Buds Originating From It Tends To Be More Abundant In The Trans-Golgi Network Compared To The Cis-Golgi
Alternative Antibody Names	Anti-Coatomer Subunit Gamma-2 antibody Anti-Gamma-2-Coat Protein antibody Anti-Gamma-2-Cop antibody Anti-COPG2 antibody

Information sourced from Uniprot.org