| Short Description : | Goat polyclonal antibody anti-Connexin 50/GJA8 (Internal) is suitable for use in ELISA research applications. |
| Applications: | Pep-ELISA |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Preliminary experiments in Human Brain (Spinal Cord) , Mouse and Rat Eye lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GJA8 |
| Gene ID: | 2703 |
| Uniprot ID: | CXA8_HUMAN |
| Accession Number: | NP_005258.2 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | TPSLCPELTTDDAR |
| Function | Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. |
| Protein Name | Gap Junction Alpha-8 ProteinConnexin-50Cx50Lens Fiber Protein Mp70 |
| Database Links | Reactome: R-HSA-190861 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell JunctionGap Junction |
| Alternative Antibody Names | Anti-Gap Junction Alpha-8 Protein antibodyAnti-Connexin-50 antibodyAnti-Cx50 antibodyAnti-Lens Fiber Protein Mp70 antibodyAnti-GJA8 antibody |
Information sourced from Uniprot.org
