| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-COMM domain-containing protein 6 (1-50 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | COMMD6 |
| Gene ID: | 170622 |
| Uniprot ID: | COMD6_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | This antibody detects endogenous levels of COMMD6 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the human COMMD6 at the amino acid range 1-50 |
| Function | Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos.the commander complex is composed of the CCC subcomplex and the retriever subcomplex. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B. Inhibits TNF-induced NFKB1 activation. |
| Protein Name | Comm Domain-Containing Protein 6 |
| Database Links | Reactome: R-HSA-8951664 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Comm Domain-Containing Protein 6 antibodyAnti-COMMD6 antibodyAnti-MSTP076 antibody |
Information sourced from Uniprot.org
