| Short Description : | Mouse monoclonal anti-Collagen III for use in IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SM0439 |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Purification: | Affinity purification |
| Dilution Range: | IHC/IF (H) 1:500-1:1500 |
| Formulation: | PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | COL3A1 |
| Gene ID: | 1281 |
| Uniprot ID: | CO3A1_HUMAN |
| Immunogen: | Recombinant protein corresponding to Human Collagen III |
| Function | Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. |
| Protein Name | Collagen Alpha-1(Iii Chain |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474244Reactome: R-HSA-1650814Reactome: R-HSA-186797Reactome: R-HSA-198933Reactome: R-HSA-2022090Reactome: R-HSA-216083Reactome: R-HSA-3000170Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-3000480Reactome: R-HSA-419037Reactome: R-HSA-8874081Reactome: R-HSA-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Collagen Alpha-1(Iii Chain antibodyAnti-COL3A1 antibody |
Information sourced from Uniprot.org
