Anti-COL8A2 antibody (611-660 aa) (STJ99330)

Name: Anti-COL8A2 antibody (611-660 aa) (STJ99330)
SKU: STJ99330
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthesized peptide derived from the human COL8A2 at the amino acid range 611-660

STJ99330

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Short Description	Rabbit polyclonal anti-Collagen alpha-2VIII chain (611-660 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	WB 1:500-2000 ELISA 1:10000-20000
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	COL8A2
Gene ID	1296
Uniprot ID	CO8A2_HUMAN
Immunogen	Synthesized peptide derived from the human COL8A2 at the amino acid range 611-660
Immunogen Region	611-660 aa
Specificity	COL8A2 Polyclonal Antibody detects endogenous levels of COL8A2

Post Translational Modifications	Proteolytically cleaved by neutrophil elastase, in vitro. Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Function	Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also a component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
Protein Name	Collagen Alpha-2(Viii Chain Endothelial Collagen
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1650814 Reactome: R-HSA-2022090 Reactome: R-HSA-216083 Reactome: R-HSA-8948216
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix Basement Membrane
Alternative Antibody Names	Anti-Collagen Alpha-2(Viii Chain antibody Anti-Endothelial Collagen antibody Anti-COL8A2 antibody

Information sourced from Uniprot.org