Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: | COL7A1 |
Gene ID: | 1294 |
Uniprot ID: | CO7A1_HUMAN |
Immunogen Region: | 2780-2944 aa |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 2780-2944 of human COL7A1 (NP_000085.1). |
Immunogen Sequence: | KGEAALTEDDIRGFVRQEMS QHCACQGQFIASGSRPLPSY AADTAGSQLHAVPVLRVSHA EEEERVPPEDDEYSEYSEYS VEEYQDPEAPWDSDDPCSLP LDEGSCTAYTLRWYHRAVTG STEACHPFVYGGCGGNANRF GTREACERRCPPRVVQSQGT GTAQD |
Post Translational Modifications | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. |
Function | Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. |
Protein Name | Collagen Alpha-1(Vii ChainLong-Chain CollagenLc Collagen |
Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474244Reactome: R-HSA-1650814Reactome: R-HSA-2022090Reactome: R-HSA-204005Reactome: R-HSA-216083Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-5694530Reactome: R-HSA-8948216 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
Alternative Antibody Names | Anti-Collagen Alpha-1(Vii Chain antibodyAnti-Long-Chain Collagen antibodyAnti-Lc Collagen antibodyAnti-COL7A1 antibody |
Information sourced from Uniprot.org