Anti-COL7A1 antibody (2780-2944 aa) (STJ11106591)

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STJ11106591
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: COL7A1
Gene ID: 1294
Uniprot ID: CO7A1_HUMAN
Immunogen Region: 2780-2944 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 2780-2944 of human COL7A1 (NP_000085.1).
Immunogen Sequence: KGEAALTEDDIRGFVRQEMS QHCACQGQFIASGSRPLPSY AADTAGSQLHAVPVLRVSHA EEEERVPPEDDEYSEYSEYS VEEYQDPEAPWDSDDPCSLP LDEGSCTAYTLRWYHRAVTG STEACHPFVYGGCGGNANRF GTREACERRCPPRVVQSQGT GTAQD
Post Translational Modifications Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Function Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.
Protein Name Collagen Alpha-1(Vii Chain
Long-Chain Collagen
Lc Collagen
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474244
Reactome: R-HSA-1650814
Reactome: R-HSA-2022090
Reactome: R-HSA-204005
Reactome: R-HSA-216083
Reactome: R-HSA-2214320
Reactome: R-HSA-3000157
Reactome: R-HSA-5694530
Reactome: R-HSA-8948216
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Basement Membrane
Alternative Antibody Names Anti-Collagen Alpha-1(Vii Chain antibody
Anti-Long-Chain Collagen antibody
Anti-Lc Collagen antibody
Anti-COL7A1 antibody

Information sourced from Uniprot.org

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