• Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Collagen XII alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of COS7 cells, using Collagen XII alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-COL12A1 antibody (1481-1530 aa) (STJ92375)

SKU:
STJ92375

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Collagen alpha-1XII chain (1481-1530 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COL12A1
Gene ID: 1303
Uniprot ID: COCA1_HUMAN
Immunogen Region: 1481-1530 aa
Specificity: COL12A1 Polyclonal Antibody detects endogenous levels of COL12A1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Collagen XII alpha1 at the amino acid range 1481-1530
Post Translational Modifications The triple-helical tail is stabilized by disulfide bonds at each end. Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates. Isoform 1 O-glycosylation.glycosaminoglycan of chondroitin-sulfate type.
Function Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.
Protein Name Collagen Alpha-1(Xii Chain
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1650814
Reactome: R-HSA-2022090
Reactome: R-HSA-8948216
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Collagen Alpha-1(Xii Chain antibody
Anti-COL12A1 antibody
Anti-COL12A1L antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance