Anti-COL11A2 antibody (210-380) (STJ112500)

Name: Anti-COL11A2 antibody (210-380) (STJ112500)
SKU: STJ112500
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ112500

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Short Description	Rabbit polyclonal COL11A2 (210-380) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	COL11A2
Gene ID	1302
Uniprot ID	COBA2_HUMAN
Immunogen Region	210-380
Immunogen Sequence	IVPGVQAAYESCEQKELECE GGQRERPQNQQPHRAQRSPQ QQPSRLHRPQNQEPQSQPTE SLYYDYEPPYYDVMTTGTTP DYQDPTPGEEEEILESSLLP PLEEEQTDLQVPPTADRFQA EEYGEGGTDPPEGPYDYTYG YGDDYREETELGPALSAETA HSGAAAHGPRG
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_542411.2).

Post Translational Modifications	Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. A disulfide-bonded peptide called proline/arginine-rich protein or PARP is released from the N-terminus during extracellular processing and is subsequently retained in the cartilage matrix from which it can be isolated in significant amounts.
Function	May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
Protein Name	Collagen Alpha-2(Xi Chain
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1650814 Reactome: R-HSA-2022090 Reactome: R-HSA-3000171 Reactome: R-HSA-8874081 Reactome: R-HSA-8948216
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Collagen Alpha-2(Xi Chain antibody Anti-COL11A2 antibody

Information sourced from Uniprot.org