| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Coilin for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R02-4B9 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: | Affinity Purified |
| Concentration: | 0.3 mg/mL |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | COIL |
| Gene ID: | 8161 |
| Uniprot ID: | COIL_HUMAN |
| Immunogen: | A synthetic peptide of human Coilin |
| Tissue Specificity | Found in all the cell types examined. |
| Post Translational Modifications | Symmetrical dimethylation of arginine residues within the RG repeat region enhances affinity for SMN, and thus localization of SMN complexes to CBs. Phosphorylated by VRK1. Phosphorylation during mitosis is associated with disassembly of CBs. |
| Function | Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs. |
| Protein Name | CoilinP80-Coilin |
| Database Links | |
| Cellular Localisation | NucleusCajal Body |
| Alternative Antibody Names | Anti-Coilin antibodyAnti-P80-Coilin antibodyAnti-COIL antibodyAnti-CLN80 antibody |
Information sourced from Uniprot.org
