Function | Plays an important role in the reorganization of the actin cytoskeleton. Regulates neuron morphogenesis and increases branching of axons and dendrites. Regulates dendrite branching in Purkinje cells. Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles. |
Protein Name | Protein Cordon-Bleu |
Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonCell ProjectionRuffleRecruited To The Cell Membrane Via Interaction With Pacsin1Colocalizes With The Actin CytoskeletonDetected Throughout The Neuron Cell BodyAs Well As In Axons And Dendrites |
Alternative Antibody Names | Anti-Protein Cordon-Bleu antibodyAnti-COBL antibodyAnti-KIAA0633 antibody |
Information sourced from Uniprot.org