| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Contactin-6 (331-380 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNTN6 |
| Gene ID: | 27255 |
| Uniprot ID: | CNTN6_HUMAN |
| Immunogen Region: | 331-380 aa |
| Specificity: | Contactin 6 Polyclonal Antibody detects endogenous levels of Contactin 6 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CNTN6 at the amino acid range 331-380 |
| Function | Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination. |
| Protein Name | Contactin-6Neural Recognition Molecule Nb-3Hnb-3 |
| Database Links | Reactome: R-HSA-447041 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Contactin-6 antibodyAnti-Neural Recognition Molecule Nb-3 antibodyAnti-Hnb-3 antibodyAnti-CNTN6 antibody |
Information sourced from Uniprot.org