| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNTN2 |
| Gene ID: | 6900 |
| Uniprot ID: | CNTN2_HUMAN |
| Immunogen Region: | 785-1012 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 785-1012 of human Contactin 2 (NP_005067.1). |
| Immunogen Sequence: | EVKIRSYNRRGDGPESLTAL VYSAEEEPRVAPTKVWAKGV SSSEMNVTWEPVQQDMNGIL LGYEIRYWKAGDKEAAADRV RTAGLDTSARVSGLHPNTKY HVTVRAYNRAGTGPASPSAN ATTMKPPPRRPPGNISWTFS SSSLSIKWDPVVPFRNESAV TGYKMLYQNDLHLTPTLHLT GKNWIEIPVPEDIGHALVQI RTTGPGGDGIPAEVHIVRNG GTSMMVEN |
| Function | In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion. |
| Protein Name | Contactin-2Axonal Glycoprotein Tag-1Axonin-1Transient Axonal Glycoprotein 1Tax-1 |
| Database Links | Reactome: R-HSA-373760Reactome: R-HSA-419037Reactome: R-HSA-447038 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorAttached To The Neuronal Membrane By A Gpi-Anchor And Is Also Released From Neurons |
| Alternative Antibody Names | Anti-Contactin-2 antibodyAnti-Axonal Glycoprotein Tag-1 antibodyAnti-Axonin-1 antibodyAnti-Transient Axonal Glycoprotein 1 antibodyAnti-Tax-1 antibodyAnti-CNTN2 antibodyAnti-AXT antibodyAnti-TAG1 antibodyAnti-TAX1 antibody |
Information sourced from Uniprot.org