• Western blot analysis of various lysates, using Contactin2 antibody (STJ11104821) at 1:20000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Anti-CNTN2 antibody (31-1012) [S4821RM] (STJ11104821)

SKU:
STJ11104821

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Contactin-2 (31-1012) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4821RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:2000-1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTN2
Gene ID: 6900
Uniprot ID: CNTN2_HUMAN
Immunogen Region: 31-1012
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-1012 of human Contactin 2 (NP_005067.1).
Immunogen Sequence: SQTTFGPVFEDQPLSVLFPE ESTEEQVLLACRARASPPAT YRWKMNGTEMKLEPGSRHQL VGGNLVIMNPTKAQDAGVYQ CLASNPVGTVVSREAILRFG FLQEFSKEERDPVKAHEGWG VMLPCNPPAHYPGLSYRWLL NEFPNFIPTDGRHFVSQTTG NLYIARTNASDLGNYSCLAT SHMDFSTKSVFSKFAQLNLA AEDTRLFAPSIKARFPAETY ALVGQQVTLECFAFGNPVP
Function In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion.
Protein Name Contactin-2
Axonal Glycoprotein Tag-1
Axonin-1
Transient Axonal Glycoprotein 1
Tax-1
Database Links Reactome: R-HSA-373760
Reactome: R-HSA-419037
Reactome: R-HSA-447038
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Attached To The Neuronal Membrane By A Gpi-Anchor And Is Also Released From Neurons
Alternative Antibody Names Anti-Contactin-2 antibody
Anti-Axonal Glycoprotein Tag-1 antibody
Anti-Axonin-1 antibody
Anti-Transient Axonal Glycoprotein 1 antibody
Anti-Tax-1 antibody
Anti-CNTN2 antibody
Anti-AXT antibody
Anti-TAG1 antibody
Anti-TAX1 antibody

Information sourced from Uniprot.org

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