| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4821RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:2000-1:20000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNTN2 |
| Gene ID: | 6900 |
| Uniprot ID: | CNTN2_HUMAN |
| Immunogen Region: | 31-1012 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-1012 of human Contactin 2 (NP_005067.1). |
| Immunogen Sequence: | SQTTFGPVFEDQPLSVLFPE ESTEEQVLLACRARASPPAT YRWKMNGTEMKLEPGSRHQL VGGNLVIMNPTKAQDAGVYQ CLASNPVGTVVSREAILRFG FLQEFSKEERDPVKAHEGWG VMLPCNPPAHYPGLSYRWLL NEFPNFIPTDGRHFVSQTTG NLYIARTNASDLGNYSCLAT SHMDFSTKSVFSKFAQLNLA AEDTRLFAPSIKARFPAETY ALVGQQVTLECFAFGNPVP |
| Function | In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion. |
| Protein Name | Contactin-2 Axonal Glycoprotein Tag-1 Axonin-1 Transient Axonal Glycoprotein 1 Tax-1 |
| Database Links | Reactome: R-HSA-373760 Reactome: R-HSA-419037 Reactome: R-HSA-447038 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Attached To The Neuronal Membrane By A Gpi-Anchor And Is Also Released From Neurons |
| Alternative Antibody Names | Anti-Contactin-2 antibody Anti-Axonal Glycoprotein Tag-1 antibody Anti-Axonin-1 antibody Anti-Transient Axonal Glycoprotein 1 antibody Anti-Tax-1 antibody Anti-CNTN2 antibody Anti-AXT antibody Anti-TAG1 antibody Anti-TAX1 antibody |
Information sourced from Uniprot.org