| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CNNM2 |
| Gene ID: | 54805 |
| Uniprot ID: | CNNM2_HUMAN |
| Immunogen Region: | 50-150 aa |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CNNM2 (NP_060119.3). |
| Immunogen Sequence: | PLLLLSCCCGAGGCAAVGEN EETVIIGLRLEDTNDVSFME GGALRVSERTRVKLRVYGQN INNETWSRIAFTEHERRRHS PGERGLGGPAPPEPDSGPQR C |
| Tissue Specificity | Widely expressed. Expressed at higher level in brain, kidney and placenta, while it is weakly expressed in skeletal muscle. In the kidney, it is expressed in the distal convoluted tubule and the thick ascending limb of Henle loop. |
| Function | Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). |
| Protein Name | Metal Transporter Cnnm2 Ancient Conserved Domain-Containing Protein 2 Cyclin-M2 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Metal Transporter Cnnm2 antibody Anti-Ancient Conserved Domain-Containing Protein 2 antibody Anti-Cyclin-M2 antibody Anti-CNNM2 antibody Anti-ACDP2 antibody |
Information sourced from Uniprot.org
