| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein cornichon homolog 3 (44-94 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNIH3 |
| Gene ID: | 149111 |
| Uniprot ID: | CNIH3_HUMAN |
| Immunogen Region: | 44-94 aa |
| Specificity: | This antibody detects endogenous levels of human CNIH3 |
| Immunogen: | Synthesized peptide derived from the human CNIH3 at the amino acid range 44-94 |
| Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. |
| Protein Name | Protein Cornichon Homolog 3Cnih-3Cornichon Family Ampa Receptor Auxiliary Protein 3 |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinAlso Localizes To The Cell Membrane Of Extrasynaptic Sites (Dendritic ShaftsSpines Of Pyramidal Cells) |
| Alternative Antibody Names | Anti-Protein Cornichon Homolog 3 antibodyAnti-Cnih-3 antibodyAnti-Cornichon Family Ampa Receptor Auxiliary Protein 3 antibodyAnti-CNIH3 antibody |
Information sourced from Uniprot.org