| Short Description : | Rabbit polyclonal CMPK1 (69-228) antibody for use in WB, IF, ICC, IP and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/IP/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CMPK1 |
| Gene ID: | 51727 |
| Uniprot ID: | KCY_HUMAN |
| Immunogen Region: | 69-228 |
| Immunogen Sequence: | LLRDERKNPDSQYGELIEKY IKEGKIVPVEITISLLKREM DQTMAANAQKNKFLIDGFPR NQDNLQGWNKTMDGKADVSF VLFFDCNNEICIERCLERGK SSGRSDDNRESLEKRIQTYL QSTKPIIDLYEEMGKVKKID ASKSVDEVFDEVVQIFDKEG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 69-228 of human CMPK1 (NP_057392.1). |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. |
| Protein Name | Ump-Cmp KinaseDeoxycytidylate KinaseCkDcmp KinaseNucleoside-Diphosphate KinaseUridine Monophosphate/Cytidine Monophosphate KinaseUmp/Cmp KinaseUmp/Cmpk |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | NucleusCytoplasmPredominantly CytoplasmicLess Than 15% Nuclear |
| Alternative Antibody Names | Anti-Ump-Cmp Kinase antibodyAnti-Deoxycytidylate Kinase antibodyAnti-Ck antibodyAnti-Dcmp Kinase antibodyAnti-Nucleoside-Diphosphate Kinase antibodyAnti-Uridine Monophosphate/Cytidine Monophosphate Kinase antibodyAnti-Ump/Cmp Kinase antibodyAnti-Ump/Cmpk antibodyAnti-CMPK1 antibodyAnti-CMK antibodyAnti-CMPK antibodyAnti-UCK antibodyAnti-UMK antibodyAnti-UMPK antibody |
Information sourced from Uniprot.org
