| Host: | Rabbit |
| Applications: | WB/IF/ICC/IP/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:200 IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CMPK1 |
| Gene ID: | 51727 |
| Uniprot ID: | KCY_HUMAN |
| Immunogen Region: | 69-228 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 69-228 of human CMPK1 (NP_057392.1). |
| Immunogen Sequence: | LLRDERKNPDSQYGELIEKY IKEGKIVPVEITISLLKREM DQTMAANAQKNKFLIDGFPR NQDNLQGWNKTMDGKADVSF VLFFDCNNEICIERCLERGK SSGRSDDNRESLEKRIQTYL QSTKPIIDLYEEMGKVKKID ASKSVDEVFDEVVQIFDKEG |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. |
| Protein Name | Ump-Cmp Kinase Deoxycytidylate Kinase Ck Dcmp Kinase Nucleoside-Diphosphate Kinase Uridine Monophosphate/Cytidine Monophosphate Kinase Ump/Cmp Kinase Ump/Cmpk |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | Nucleus Cytoplasm Predominantly Cytoplasmic Less Than 15% Nuclear |
| Alternative Antibody Names | Anti-Ump-Cmp Kinase antibody Anti-Deoxycytidylate Kinase antibody Anti-Ck antibody Anti-Dcmp Kinase antibody Anti-Nucleoside-Diphosphate Kinase antibody Anti-Uridine Monophosphate/Cytidine Monophosphate Kinase antibody Anti-Ump/Cmp Kinase antibody Anti-Ump/Cmpk antibody Anti-CMPK1 antibody Anti-CMK antibody Anti-CMPK antibody Anti-UCK antibody Anti-UMK antibody Anti-UMPK antibody |
Information sourced from Uniprot.org