| Tissue Specificity | Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturation and differentiation in thymus and fetal liver. |
| Function | Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor. |
| Protein Name | C-Maf-Inducing ProteinC-MipTruncated C-Maf-Inducing ProteinTc-Mip |
| Cellular Localisation | NucleusCytoplasmIsoform 2 Is Translocated To The Nucleus And Is Specifically Recruited During Minimal Change Nephrotic Syndrome (Mcns)Detected In Nuclear And Cytoplasmic Compartments During Mcns RelapseExpressed In Cytoplasm Only During Mcns Remission And Absent In Normal Patients |
| Alternative Antibody Names | Anti-C-Maf-Inducing Protein antibodyAnti-C-Mip antibodyAnti-Truncated C-Maf-Inducing Protein antibodyAnti-Tc-Mip antibodyAnti-CMIP antibodyAnti-KIAA1694 antibodyAnti-TCMIP antibody |
Information sourced from Uniprot.org
