Anti-CMA1 antibody (148-247) [S1MR] (STJ11101341)

Name: Anti-CMA1 antibody (148-247) [S1MR] (STJ11101341)
SKU: STJ11101341
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11101341

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Short Description	Rabbit monoclonal Mast Cell Chymase (148-247) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S1MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:6000 IHC-P:1:100-1:800 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CMA1
Gene ID	1215
Uniprot ID	CMA1_HUMAN
Immunogen Region	148-247
Immunogen Sequence	GWGRTGVLKPGSDTLQEVKL RLMDPQACSHFRDFDHNLQL CVGNPRKTKSAFKGDSGGPL LCAGVAQGIVSYGRSDAKPP AVFTRISHYRPWINQILQAN
Specificity	A synthetic peptide corresponding to a sequence within amino acids 148-247 of human Mast Cell Chymase (CMA1) (CMA1) (P23946).

Tissue Specificity	Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions.
Function	Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
Protein Name	Chymase Alpha-Chymase Mast Cell Protease I
Database Links	Reactome: R-HSA-1433557 Reactome: R-HSA-1592389 Reactome: R-HSA-2022377
Cellular Localisation	Secreted Cytoplasmic Granule Mast Cell Granules
Alternative Antibody Names	Anti-Chymase antibody Anti-Alpha-Chymase antibody Anti-Mast Cell Protease I antibody Anti-CMA1 antibody Anti-CYH antibody Anti-CYM antibody

Information sourced from Uniprot.org