| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CLVS2 |
| Gene ID: | 134829 |
| Uniprot ID: | CLVS2_HUMAN |
| Immunogen Region: | 265-327 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 265-327 of human CLVS2 (NP_001010852.2). |
| Immunogen Sequence: | LLDHEYDDDSEYNVDSYSMP VKEVEKELSPKSMKRSQSVV DPTVLKRMDKNEEENMQPLL SLD |
| Function | Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). |
| Protein Name | Clavesin-2Retinaldehyde-Binding Protein 1-Like 2Clathrin Vesicle-Associated Sec14 Protein 2 |
| Database Links | Reactome: R-HSA-432720 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane ProteinCytoplasmic VesicleClathrin-Coated VesicleEarly Endosome Membrane |
| Alternative Antibody Names | Anti-Clavesin-2 antibodyAnti-Retinaldehyde-Binding Protein 1-Like 2 antibodyAnti-Clathrin Vesicle-Associated Sec14 Protein 2 antibodyAnti-CLVS2 antibodyAnti-C6orf212 antibodyAnti-C6orf213 antibodyAnti-RLBP1L2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of various lysates using [KO Validated] SHMT2 Rabbit polyclonal antibody (STJ25526) at 1:400 dilution incubated overnight at 4 °C. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic KitExposure time: 30 s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/100514/387105/STJ25526_1__79760.1713156306.jpg?c=1 "Western blot analysis of various lysates using [KO Validated] SHMT2 Rabbit polyclonal antibody (STJ25526) at 1:400 dilution incubated overnight at 4 °C. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic KitExposure time: 30 s.")
