![Western blot analysis of lysates from wild type (WT) and CLUH knockout (KO) 293T cells, using [KO Validated] CLUH Rabbit polyclonal antibody (STJ11100855) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/89789/358260/STJ11100855_1__37263.1713122599.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CLUH knockout (KO) 293T cells, using [KO Validated] CLUH Rabbit polyclonal antibody (STJ11100855) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
![Western blot analysis of lysates from wild type (WT) and CLUH knockout (KO) 293T cells, using [KO Validated] CLUH Rabbit polyclonal antibody (STJ11100855) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/89789/358260/STJ11100855_1__37263.1713122599.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CLUH knockout (KO) 293T cells, using [KO Validated] CLUH Rabbit polyclonal antibody (STJ11100855) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:4000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CLUH |
| Gene ID: | 23277 |
| Uniprot ID: | CLU_HUMAN |
| Immunogen Region: | 1120-1309 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1120-1309 of human CLUH (NP_056044.3). |
| Immunogen Sequence: | YDLSLRFLENALAVSTKYHG PKALKVALSHHLVARVYESK AEFRSALQHEKEGYTIYKTQ LGEDHEKTKESSEYLKCLTQ QAVALQRTMNEIYRNGSSAN IPPLKFTAPSMASVLEQLNV INGILFIPLSQKDLENLKAE VARRHQLQEASRNRDRAEEP MATEPAPAGAPGDLGSQPPA AKDPSPSVQG |
| Function | mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis. |
| Protein Name | Clustered Mitochondria Protein Homolog |
| Cellular Localisation | CytoplasmCytoplasmic GranuleA Fraction Colocalizes With Tyrosinated Tubulin And Can Be Detected Close To Mitochondria |
| Alternative Antibody Names | Anti-Clustered Mitochondria Protein Homolog antibodyAnti-CLUH antibodyAnti-KIAA0664 antibody |
Information sourced from Uniprot.org