| Function | Scramblase that mediates the translocation of glucosaminylphosphatidylinositol (alpha-D-GlcN-(1-6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a lipid glycoconjugate involved in post-translational modification of proteins. Can also translocate 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (phosphatidylinositol or PI), as well as several other phospholipids (1,2-diacyl-sn-glycero-3-phosphocholine, 1,2-diacyl-sn-glycero-3-phosphoethanolamine), and N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) in vitro. |
| Protein Name | Lipid Scramblase Clptm1lCisplatin Resistance-Related Protein 9Crr9pCleft Lip And Palate Transmembrane Protein 1-Like ProteinClptm1-Like Protein |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Lipid Scramblase Clptm1l antibodyAnti-Cisplatin Resistance-Related Protein 9 antibodyAnti-Crr9p antibodyAnti-Cleft Lip And Palate Transmembrane Protein 1-Like Protein antibodyAnti-Clptm1-Like Protein antibodyAnti-CLPTM1L antibodyAnti-CRR9 antibody |
Information sourced from Uniprot.org
