| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Cleaved-Integrin alpha-E-Arg177, Light Chain (177-178) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITGAE |
| Gene ID: | 3682 |
| Uniprot ID: | ITAE_HUMAN |
| Immunogen Region: | 177-178 |
| Specificity: | This antibody detects endogenous levels of Human ITGAE (light chain, Cleaved-Arg177, protein was cleaved amino acid sequence between 177-178 ) |
| Immunogen: | Synthesized peptide derived from human ITGAE (light chain, Cleaved-Arg177) |
| Tissue Specificity | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
| Protein Name | Integrin Alpha-EHml-1 AntigenIntegrin Alpha-IelMucosal Lymphocyte 1 AntigenCd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain |
| Database Links | Reactome: R-HSA-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-E antibodyAnti-Hml-1 Antigen antibodyAnti-Integrin Alpha-Iel antibodyAnti-Mucosal Lymphocyte 1 Antigen antibodyAnti-Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain antibodyAnti-ITGAE antibody |
Information sourced from Uniprot.org
