• Western blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24h, using FA13A (Cleaved-Gly39) Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-Cleaved-F13A1-G39 antibody (20-69 aa) (STJ90052)

SKU:
STJ90052

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cleaved-Coagulation factor XIII A chain-G39 (20-69 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: F13A1
Gene ID: 2162
Uniprot ID: F13A_HUMAN
Immunogen Region: 20-69 aa
Specificity: Cleaved-Factor XIIIa (G39) Polyclonal Antibody detects endogenous levels of fragment of activated Factor XIIIa protein resulting from cleavage adjacent to G39.
Immunogen: The antiserum was produced against synthesized peptide derived from the human FA13A at the amino acid range 20-69
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Protein Name Coagulation Factor Xiii A Chain
Coagulation Factor Xiiia
Protein-Glutamine Gamma-Glutamyltransferase A Chain
Transglutaminase A Chain
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140875
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Secreted
Secreted Into The Blood Plasma
Cytoplasmic In Most Tissues
But Also Secreted In The Blood Plasma
Alternative Antibody Names Anti-Coagulation Factor Xiii A Chain antibody
Anti-Coagulation Factor Xiiia antibody
Anti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibody
Anti-Transglutaminase A Chain antibody
Anti-F13A1 antibody
Anti-F13A antibody

Information sourced from Uniprot.org

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