• Western blot analysis of lysates from A549 cells, treated with etoposide 25uM 24h, using Collagen III alpha1 (Cleaved-Gly1221) Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Cleaved-COL3A1 (G1221) Polyclonal Antibody

Anti-Cleaved-COL3A1-G1221 antibody (1172-1221 aa) (STJ90049)

SKU:
STJ90049

Current Stock:
Host: Rabbit
Applications: ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cleaved-Collagen alpha-1III chain-G1221 (1172-1221 aa) is suitable for use in ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COL3A1
Gene ID: 1281
Uniprot ID: CO3A1_HUMAN
Immunogen Region: 1172-1221 aa
Specificity: Cleaved-COL3A1 (G1221) Polyclonal Antibody detects endogenous levels of fragment of activated COL3A1 protein resulting from cleavage adjacent to G1221.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Collagen III alpha1 at the amino acid range 1172-1221
Function Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
Protein Name Collagen Alpha-1(Iii Chain
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474244
Reactome: R-HSA-1650814
Reactome: R-HSA-186797
Reactome: R-HSA-198933
Reactome: R-HSA-2022090
Reactome: R-HSA-216083
Reactome: R-HSA-3000170
Reactome: R-HSA-3000171
Reactome: R-HSA-3000178
Reactome: R-HSA-3000480
Reactome: R-HSA-419037
Reactome: R-HSA-8874081
Reactome: R-HSA-8948216
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Collagen Alpha-1(Iii Chain antibody
Anti-COL3A1 antibody

Information sourced from Uniprot.org

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