| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Cleaved-Collagen alpha-1XV chain-Asn1212 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | COL15A1 |
| Gene ID: | 1306 |
| Uniprot ID: | COFA1_HUMAN |
| Specificity: | This antibody detects endogenous levels of Human, Mouse Collagen XV Alpha 1 (Cleaved-Asn1212, protein was cleaved amino acid sequence between 1211-1212 ) |
| Immunogen: | Synthesized peptide derived from the human Collagen XV Alpha 1 (Cleaved-Asn1212) |
| Post Translational Modifications | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. O-glycosylated.with core 1 or possibly core 8 glycans. Contains chondroitin sulfate. |
| Function | Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. Restin potently inhibits angiogenesis. |
| Protein Name | Collagen Alpha-1(Xv Chain Cleaved Into - RestinEndostatin-XvRelated To EndostatinRestin-I - Restin-2Restin-Ii - Restin-3Restin-Iii - Restin-4Restin-Iv |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1650814Reactome: R-HSA-2022090Reactome: R-HSA-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Collagen Alpha-1(Xv Chain Cleaved Into - Restin antibodyAnti-Endostatin-Xv antibodyAnti-Related To Endostatin antibodyAnti-Restin-I - Restin-2 antibodyAnti-Restin-Ii - Restin-3 antibodyAnti-Restin-Iii - Restin-4 antibodyAnti-Restin-Iv antibodyAnti-COL15A1 antibody |
Information sourced from Uniprot.org