• Western blot analysis of lysates from 293 and HeLa cells, treated with etoposide 25uM 1h, using C1S (heavy chain, Cleaved-Arg437) Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Cleaved-C1s HC (R437) Polyclonal Antibody

Anti-Cleaved-C1S-R437 antibody (388-437 aa) (STJ90019)

SKU:
STJ90019

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cleaved-Complement C1s subcomponent-R437 (388-437 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C1S
Gene ID: 716
Uniprot ID: C1S_HUMAN
Immunogen Region: 388-437 aa
Specificity: Cleaved-C1s HC (R437) Polyclonal Antibody detects endogenous levels of fragment of activated C1s HC protein resulting from cleavage adjacent to R437.
Immunogen: The antiserum was produced against synthesized peptide derived from the human C1S at the amino acid range 388-437
Function C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
Protein Name Complement C1s Subcomponent
C1 Esterase
Complement Component 1 Subcomponent S Cleaved Into - Complement C1s Subcomponent Heavy Chain - Complement C1s Subcomponent Light Chain
Database Links Reactome: R-HSA-166663
Reactome: R-HSA-173623
Reactome: R-HSA-977606
Alternative Antibody Names Anti-Complement C1s Subcomponent antibody
Anti-C1 Esterase antibody
Anti-Complement Component 1 Subcomponent S Cleaved Into - Complement C1s Subcomponent Heavy Chain - Complement C1s Subcomponent Light Chain antibody
Anti-C1S antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance