| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CLDN2 (30-230) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CLDN2 |
| Gene ID: |
9075 |
| Uniprot ID: |
CLD2_HUMAN |
| Immunogen Region: |
30-230 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human CLDN2 (NP_001164566.1). |
| Immunogen Sequence: |
WKTSSYVGASIVTAVGFSKG LWMECATHSTGITQCDIYST LLGLPADIQAAQAMMVTSSA ISSLACIISVVGMRCTVFCQ ESRAKDRVAVAGGVFFILGG LLGFIPVAWNLHGILRDFYS PLVPDSMKFEIGEALYLGII SSLFSLIAGIILCFSCSSQR NRSNYYDAYQAQPLATRSSP RPGQPPKVKSEFNSYSLTGY V |
| Post Translational Modifications | The disulfide bond is necessary for pore formation, but is not required for correct protein trafficking. |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
| Protein Name | Claudin-2Sp82 |
| Database Links | Reactome: R-HSA-420029 |
| Cellular Localisation | Cell JunctionTight JunctionCell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Claudin-2 antibodyAnti-Sp82 antibodyAnti-CLDN2 antibodyAnti-PSEC0059 antibodyAnti-SP82 antibodyAnti-UNQ705 antibodyAnti-PRO1356 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
