| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Claudin-17 (150-230 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CLDN17 |
| Gene ID: | 26285 |
| Uniprot ID: | CLD17_HUMAN |
| Immunogen Region: | 150-230 aa |
| Specificity: | Claudin-17 Polyclonal Antibody detects endogenous levels of Claudin-17 protein. |
| Immunogen: | Synthesized peptide derived from Claudin-17 at the amino acid range 150-230 |
| Function | Channel-forming tight junction protein with selectivity for anions, including chloride and hydrogencarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in paracellular reabsorption of filtered anions. Does not affect water permeability. |
| Protein Name | Claudin-17 |
| Database Links | Reactome: R-HSA-420029 |
| Cellular Localisation | Cell JunctionTight JunctionBasolateral Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Claudin-17 antibodyAnti-CLDN17 antibodyAnti-UNQ758 antibodyAnti-PRO1489 antibody |
Information sourced from Uniprot.org