| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-H+/Cl-exchange transporter 7 (10-59 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CLCN7 |
| Gene ID: |
1186 |
| Uniprot ID: |
CLCN7_HUMAN |
| Immunogen Region: |
10-59 aa |
| Specificity: |
CLC-7 Polyclonal Antibody detects endogenous levels of CLC-7 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human CLCN7 at the amino acid range 10-59 |
| Function | Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. |
| Protein Name | H(+/Cl(- Exchange Transporter 7Chloride Channel 7 Alpha SubunitChloride Channel Protein 7Clc-7 |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-H(+/Cl(- Exchange Transporter 7 antibodyAnti-Chloride Channel 7 Alpha Subunit antibodyAnti-Chloride Channel Protein 7 antibodyAnti-Clc-7 antibodyAnti-CLCN7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
