Anti-CLCN4 antibody (221-270 aa) (STJ92324)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CLCN4 at the amino acid range 221-270
General Information
| Short Description | Rabbit polyclonal anti-H+/Cl-exchange transporter 4 (221-270 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLCN4 |
| Gene ID | 1183 |
| Uniprot ID | CLCN4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CLCN4 at the amino acid range 221-270 |
| Immunogen Region | 221-270 aa |
| Specificity | CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein. |
Additional Info
| Function | Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. |
| Protein Name | H(+/Cl(- Exchange Transporter 4Chloride Channel Protein 4Clc-4Chloride Transporter Clc-4 |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Early Endosome MembraneMulti-Pass Membrane ProteinLate Endosome MembraneEndoplasmic Reticulum MembraneLysosome MembraneRecycling Endosome MembraneLocalizes To Late Endosome MembraneLysosome Membrane And Recycling Endosome Membrane In The Presence Of Clcn3 |
| Alternative Antibody Names | Anti-H(+/Cl(- Exchange Transporter 4 antibodyAnti-Chloride Channel Protein 4 antibodyAnti-Clc-4 antibodyAnti-Chloride Transporter Clc-4 antibodyAnti-CLCN4 antibody |
Information sourced from Uniprot.org