Host: |
Rabbit |
Applications: |
WB/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-H+/Cl-exchange transporter 4 (221-270 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CLCN4 |
Gene ID: |
1183 |
Uniprot ID: |
CLCN4_HUMAN |
Immunogen Region: |
221-270 aa |
Specificity: |
CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human CLCN4 at the amino acid range 221-270 |
Function | Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. |
Protein Name | H(+/Cl(- Exchange Transporter 4Chloride Channel Protein 4Clc-4Chloride Transporter Clc-4 |
Database Links | Reactome: R-HSA-2672351 |
Cellular Localisation | Early Endosome MembraneMulti-Pass Membrane ProteinLate Endosome MembraneEndoplasmic Reticulum MembraneLysosome MembraneRecycling Endosome MembraneLocalizes To Late Endosome MembraneLysosome Membrane And Recycling Endosome Membrane In The Presence Of Clcn3 |
Alternative Antibody Names | Anti-H(+/Cl(- Exchange Transporter 4 antibodyAnti-Chloride Channel Protein 4 antibodyAnti-Clc-4 antibodyAnti-Chloride Transporter Clc-4 antibodyAnti-CLCN4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance