| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cyclin-dependent kinase 2-interacting protein (160-210 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CINP |
| Gene ID: |
51550 |
| Uniprot ID: |
CINP_HUMAN |
| Immunogen Region: |
160-210 aa |
| Specificity: |
This antibody detects endogenous levels of human CINP |
| Immunogen: |
Synthesized peptide derived from the human CINP at the amino acid range 160-210 |
| Function | Component of the DNA replication complex, which interacts with two kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling in response to DNA damage. Also involved in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles. Promotes maturation of pre-60S ribosome together with AFG2A, AFG2B and AIRIM. |
| Protein Name | Cyclin-Dependent Kinase 2-Interacting ProteinCdk2-Interacting Protein |
| Cellular Localisation | NucleusBinds To Nuclear Under G1 ConditionsAnd Dissociates From Chromatin With The Start Of Dna Replication |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 2-Interacting Protein antibodyAnti-Cdk2-Interacting Protein antibodyAnti-CINP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
