Anti-CIAO3 antibody (387-436) (STJ94345)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human NARFL. AA range:387-436
STJ94345
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General Information

Short DescriptionRabbit polyclonal anti-Cytosolic iron-sulfur assembly component 3 (387-436) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCIAO3
Gene ID64428
Uniprot IDCIAO3_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from human NARFL. AA range:387-436
Immunogen Region387-436
SpecificityNARFL Polyclonal Antibody detects endogenous levels of NARFL protein.

Additional Info

Tissue Specificity Widely expressed.
Function Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
Protein Name Cytosolic Iron-Sulfur Assembly Component 3
Cytosolic Fe-S Cluster Assembly Factor Narfl
Iron-Only Hydrogenase-Like Protein 1
Iop1
Nuclear Prelamin A Recognition Factor-Like Protein
Protein Related To Narf
Database Links Reactome: R-HSA-2564830
Cellular Localisation
Alternative Antibody Names Anti-Cytosolic Iron-Sulfur Assembly Component 3 antibody
Anti-Cytosolic Fe-S Cluster Assembly Factor Narfl antibody
Anti-Iron-Only Hydrogenase-Like Protein 1 antibody
Anti-Iop1 antibody
Anti-Nuclear Prelamin A Recognition Factor-Like Protein antibody
Anti-Protein Related To Narf antibody
Anti-CIAO3 antibody
Anti-NARFL antibody
Anti-PRN antibody

Information sourced from Uniprot.org

Citations

Product Review