| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc. |
| Protein Name | Carbohydrate Sulfotransferase 7Chondroitin 6-Sulfotransferase 2C6st-2Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 5Gst-5N-Acetylglucosamine 6-O-Sulfotransferase 4Glcnac6st-4Gn6st-4 |
| Database Links | Reactome: R-HSA-2022870 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 7 antibodyAnti-Chondroitin 6-Sulfotransferase 2 antibodyAnti-C6st-2 antibodyAnti-Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 5 antibodyAnti-Gst-5 antibodyAnti-N-Acetylglucosamine 6-O-Sulfotransferase 4 antibodyAnti-Glcnac6st-4 antibodyAnti-Gn6st-4 antibodyAnti-CHST7 antibody |
Information sourced from Uniprot.org
