| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures. May also have activity toward O-linked sugars of mucin-type acceptors. |
| Protein Name | Carbohydrate Sulfotransferase 5Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 4Gst4Intestinal N-Acetylglucosamine-6-O-SulfotransferaseI-Glcnac6stIntestinal Glcnac-6-SulfotransferaseMign6stN-Acetylglucosamine 6-O-Sulfotransferase 3Glcnac6st-3Gn6st-3 |
| Database Links | Reactome: R-MMU-2022854 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinGolgi MembraneEarly Secretory Pathway |
| Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 5 antibodyAnti-Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 4 antibodyAnti-Gst4 antibodyAnti-Intestinal N-Acetylglucosamine-6-O-Sulfotransferase antibodyAnti-I-Glcnac6st antibodyAnti-Intestinal Glcnac-6-Sulfotransferase antibodyAnti-Mign6st antibodyAnti-N-Acetylglucosamine 6-O-Sulfotransferase 3 antibodyAnti-Glcnac6st-3 antibodyAnti-Gn6st-3 antibodyAnti-Chst5 antibodyAnti-Gst4 antibody |
Information sourced from Uniprot.org
