Post Translational Modifications | N-glycosylated.required for activity and stability. |
Function | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor. |
Protein Name | Carbohydrate Sulfotransferase 11Chondroitin 4-O-Sulfotransferase 1Chondroitin 4-Sulfotransferase 1C4s-1C4st-1C4st1 |
Database Links | Reactome: R-HSA-2022870 |
Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 11 antibodyAnti-Chondroitin 4-O-Sulfotransferase 1 antibodyAnti-Chondroitin 4-Sulfotransferase 1 antibodyAnti-C4s-1 antibodyAnti-C4st-1 antibodyAnti-C4st1 antibodyAnti-CHST11 antibody |
Information sourced from Uniprot.org