| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHRM1 |
| Gene ID: | 1128 |
| Uniprot ID: | ACM1_HUMAN |
| Immunogen Region: | 251-350 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 251-350 of human CHRM1 (NP_000729.2). |
| Immunogen Sequence: | SPETPPGRCCRCCRAPRLLQ AYSWKEEEEEDEGSMESLTS SEGEEPGSEVVIKMPMVDPE AQAPTKQPPRSSPNTVKRPT KKGRDRAGKGQKPRGKEQLA |
| Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. |
| Protein Name | Muscarinic Acetylcholine Receptor M1 |
| Database Links | Reactome: R-HSA-390648Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Muscarinic Acetylcholine Receptor M1 antibodyAnti-CHRM1 antibody |
Information sourced from Uniprot.org