Anti-CHRDL1 antibody [SAA1791] (STJA0020219)

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STJA0020219
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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Chordin-Like Protein 1 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1791
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: CHRDL1
Gene ID: 91851
Uniprot ID: CRDL1_HUMAN
Function Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation. May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Protein Name Chordin-Like Protein 1
Neuralin-1
Neurogenesin-1
Ventroptin
Database Links Reactome: R-HSA-201451
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Antibody Names Anti-Chordin-Like Protein 1 antibody
Anti-Neuralin-1 antibody
Anti-Neurogenesin-1 antibody
Anti-Ventroptin antibody
Anti-CHRDL1 antibody
Anti-NRLN1 antibody

Information sourced from Uniprot.org